Zymes llc. What is CoQ10?
Coenzyme Q10 Biosynthesis: How is it Made by the Body? Every cell in the body is capable of coenzyme Q10 biosynthesis. Each cell makes a different amount, depending upon its tissue type and energy requirements. Cells in organs that are very active and have high energy requirements such as the heart, brain and liver make the most coenzyme Q10 and contain the highest amounts. Unfortunately, the body’s ability to make coenzyme Q10 declines with age. Peak production occurs at about age 21 and gradually declines thereafter. 1 It has been shown that coenzyme Q10 levels fall with age in both heart and brain tissue as illustrated in the figure below. In addition, body stores of coenzyme Q10 may be reduced by a variety of external factors such as certain medications, hormone levels, alcohol consumption, nutritional depletion, strenuous exercise, elevated cholesterol and triglycerides, and stressors such as illness and extreme cold. Due to the reduced production of coenzyme Q10 with age, in comb