Why would a significant percentage of children with autism have low values of cholesterol?
There are multiple reasons including reduced intake in the diet, reduced digestion and absorption, reduced synthesis by the tissues of the body, and increased elimination in the bile. Dysbiosis, insufficient production of digestive enzymes, and intestinal inflammation can lead to reduced cholesterol production. In addition, diarrhea causes any ingested cholesterol to pass too quickly through the intestine to be efficiently absorbed. In addition, the synthesis of cholesterol might be deficient because of genetic factors in any one of the 26 biochemical steps required for cholesterol synthesis in the body.
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