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Why can varicella be kept up to 72 hours at nonfreezing temps. Previous info given said keep frozen until use?

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Why can varicella be kept up to 72 hours at nonfreezing temps. Previous info given said keep frozen until use?

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The Varivax package insert states that the vaccine may be stored at refrigerator temperature for up to 72 hours before reconstitution, but can be kept at room temperature for only 30 minutes after reconstitution. Once the vaccine has thawed it should not be refrozen.

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