Whats Wrong With the WHI Study?
The outcome of the study was not a surprise to many people. The average age of the women in the study was 63; there was therefore a high rate of preexisting disease, which may have skewed the health risks. Further, the women involved in the study may not have been truly eligible for hormone replacement therapy. A large flaw in the study was that it did not take into account any physiological differences between the women and gave them identical doses of hormones. Everyone’s different. Everyone has different hormonal needs and responds differently to hormone therapy. Also, the estrogen in the Prempro, called CEE or Premarin, does not have the same ratios of estrogens as human physiology, as seen in the table. Most importantly, the WHI study used Prempro, made from both synthetic estrogen and synthetic progesterone, but the culprit for the increased health risks was the synthetic progesterone. Another study found that using only synthetic estrogen (CEE) compared with placebo was actually
Related Questions
- If something goes wrong while doing the internship or study immersion, will I be able to communicate with MA in International Studies directors and seek help/guidance?
- What were the main findings in the WHI study on estrogen-plus-progestin?
- How does this new information affect women in the WHI study of estrogen alone?
