What is WHIMS?
WHIMS is a sub-study within the Womens Health Initiative (WHI). In the past, some studies reported a positive association between use of hormone therapy and cognitive protection, while others failed to find protective effects. Because of these inconsistent results, a large, controlled randomized clinical trial of hormone treatment was needed. Only women who joined the Hormone Program and were 65 years of age and older when they joined, were invited to participate in WHIMS. The purpose of WHIMS was to find out if taking hormones (estrogen alone or estrogen plus progestin) would prevent dementia or slow the decline of cognitive function in postmenopausal women.