What is the prognosis of myelofibrosis?
In general, the survival of patients with idiopathic myelofibrosis seems to a large extent programmed by their presenting findings and is not very much altered by therapy. Approximately 60% of patients with idiopathic myelofibrosis live 5 years. There is a significant cohort of patients who live 10 years or more. Patients with idiopathic myelofibrosis who tend to do very well include those whose presenting hemoglobin levels are greater than 10 gm/dl, platelet counts greater than 100×3/ul and only modest enlargement of the liver. Spleen size and sex seem to have no prognostic significance.5.
In general, the survival of patients with idiopathic myelofibrosis seems to a large extent programmed by their presenting findings and is not very much altered by therapy. Approximately 60% of patients with idiopathic myelofibrosis live 5 years. There is a significant cohort of patients who live 10 years or more. Patients with idiopathic myelofibrosis who tend to do very well include those whose presenting hemoglobin levels are greater than 10 gm/dl, platelet counts greater than 100×3/ul and only modest enlargement of the liver. Spleen size and sex seem to have no prognostic significance. 5.
