What Is Positional Cloning?
Positional cloning is a technique which is used in genetic screening to identify specific areas of interest in the genome, and then determine what they do. This type of genetic screening is sometimes referred to as reverse genetics, because researchers start by figuring out where a gene is, and then they determine what it does, in contrast with methods which start by determining the function of a gene and then finding it in the genome. Genes related to conditions such as Huntington’s Disease and cystic fibrosis have been identified with this technique.
