What is Genome@Home (G@H)?
It is a distributed computing project run by an academic institution (the Pande Group, at Stanford University’s Chemistry Department), which is a non-profit institution dedicated to science research and education. The aim is to design new sequences for existing 3-D protein structures, which come from real genomes.The protein structure files that are sent out as work contain the Cartesian atomic coordinates of a protein. The Genome@home data will be used to: – Try to unravel a fundamental issue in the “protein folding problem” (which itself lies at the heart of a huge amount of modern biomedical research): the fact that thousands of different sequences can all form the same three-dimensional structure. – Predict the functions of newly discovered genes and protein structures. Modern approaches to structural biology, known as “proteomics” or “structural genomics”, often solve protein structures without knowing what the proteins do. Because techniques for function prediction tend to work b
