What is delayed type hypersensitivity?
This is the only class of hypersensitive reactions to be triggered by antigen-specific T cells, which are linked to inflammation. This type of hypersensitivity is often called “delayed type” as the reaction takes two to three days to develop. Unlike the other types, it is not antibody mediated but rather is a type of cell-mediated response. T cells belong to a group of white blood cells known as lymphocytes and play a central role in cell-mediated immunity. Antigen-specific T cells provides the immune system with “memory” against past infections. TARL also protected joint destruction based on the evidence of reducing the histopathological scores (which are the total scores based on the sum of peribronchial, perivascular, interstitial, and alveolar inflammation). The researchers thus conclude that TARL is a potential therapeutic agent for rheumatoid arthritis that suppresses inflammation and protects joints from destruction. [J Ethnopharmacol.
