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What is “age dependent penetrance?

April 26, 2017age dependent penetrance

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What is “age dependent penetrance?

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PHPT affects older Keeshonden with what is known as “age dependent penetrance.” This means that the test does not identify clinical disease at the time of testing; it indicates the presence of the defective gene, or the genetic potential to develop the disease later in life. The vast majority of Keeshonden with the defective gene will develop PHPT if they live long enough.