What are the normal values for serum FLC?
Publications from Birmingham University and The Mayo Clinic have shown similar results. The data from The Mayo Clinic contains results from older people and indicates that serum FLC concentrations increase in normal individuals aged >70 years due to deteriorating glomerular filtration. Results from patients should be compared with the age-matched, normal range data. However, all laboratories should make some assessment of normal ranges in their own laboratories since there will be minor variations resulting from differences in race, age, exposure to infections, etc. Normal ranges are usually established by reference to standards (comprising purified proteins) that have been agreed by International committees. Freelite is a unique test and since there is no international agreement at present no definitive statement on the accuracy of the normal ranges can be made. In time, agreed reference materials will be manufactured, International agreement established, and the normal ranges will th
