Is there a certain color that has been proven to be least tiring to the eye on web page backgrounds?
I don’t know if any research has been done on web pages specifically, but it is well established that dark text on a white background is least fatiguing for extended amounts of reading. That’s why most computer systems arrange the text that way. For presentations in a darkened room (and short amounts of text), bright text on a dark background is easiest to read.