Is GPS 2.1 accurate?
Yes, but not all. Prediction of kinase-specific phosphorylation sites is a greatly difficult problem. If the training data is enough, the prediction is satisfying and accurate. But for many protein kinases, the training data set are very limited, to make the performance lower. For kinase-specific prediction, no algorithm or approach could reach the best performances for all of the protein kinases. However, by comparison, the prediction performances of GPS are better or at least comparable with previous tools. And also, we will updated the GPS routinely to make it more accurate and powerful.
