How long does the high from methamphetamine last?
It depends on how it is used. When injected or taken by mouth, the effects of the drug last about 6-8 hours. Smoking methamphetamine may produce effects that last 10-12 hours. After the effects of the drug have worn off, users are left feeling tired and depressed. Some use of the drug continuously over a period of days or weeks in a “binge and crash” pattern, inviting serious health risks, and leading to drug dependency.