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How does LYRICA work?

April 26, 2017lyrica

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How does LYRICA work?

2 Answers

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A7: In animal models, LYRICA was found to selectively bind to the alpha2-delta (A2D) subunit of voltage-gated calcium channels. In vitro, LYRICA reduced the excessive release of several neurotransmitters, possibly by modulation of calcium channel influx. It is active only in hyperexcited neurons. LYRICA is not a vascular calcium channel blocker and does not significantly affect blood pressure or cardiac function.

0

Posted

In animal models, LYRICA was found to selectively bind to the alpha 2 -delta (A2D) subunit of voltage-gated calcium channels. In vitro , LYRICA reduced the excessive release of several neurotransmitters, possibly by modulation of calcium channel influx. It is active only in hyperexcited neurons. LYRICA is not a vascular calcium channel blocker and does not significantly affect blood pressure or cardiac function.