How does Fen-Phen work?
Fenfluramine (“fen”) triggers the release of serotonin – one of the many natural chemicals stored in the nerves which facilitate a nerve cell’s ability to send messages to another nerve cell in the system. Drugs which enhance serotonin levels are thought to provide a feeling of fullness. As an appetite suppressant, phentermine (“phen”) works by releasing norepinephrine, similar to adrenalin, into the system. Norepinephrine acts as a stimulant and also leaves the user with the feeling of fullness.