How do People Inherit Myotonia Dystrophy?
Myotonic dystrophy is inherited in an autosomal dominant pattern, which means one copy of the altered gene is sufficient to cause the disorder. In most cases, an affected person has one affected parent. As type 1 myotonic dystrophy is passed from one generation to the next, the disorder generally begins earlier in life and signs and symptoms become more severe. This phenomenon is called anticipation. In type 1 myotonic dystrophy, anticipation is caused by an increase in the length of the unstable region in the DMPK gene. In type 2 myotonic dystrophy, a longer unstable region in the ZNF9 gene does not appear to influence the age of onset of the disorder. As with many inherited disorders, the degree of manifestation of the disorder, i.e the severity of the disorder is determined by the quality of diet and lifestyle. Genetotrophics The important interrelationship between food and the genes was first called the “genetotrophic concept” by Roger J. Williams, PhD. Dr. Williams, the discoverer
