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Equivalence and Non-Inferiority Tests Q. Is there guidance on how to use exact confidence intervals for tests of equivalence and non-inferiority?

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Equivalence and Non-Inferiority Tests Q. Is there guidance on how to use exact confidence intervals for tests of equivalence and non-inferiority?

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A. Using a confidence interval to derive an exact p-value for a test requires some thought. Many people get confused about the choice of confidence level, and which tail of the confidence interval to use, when trying to derive a p-value from a confidence interval. We have to also worry about whether it is a one-sided or two-sided p-value. It is simpler just to run the exact tests of non-inferiority and equivalence that StatXact now provides.

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