Zoloft and Sex Drive Question: Does any research indicate that 100mg of Zoloft daily can result in sexual dysfunction and short term memory loss in men?
Zoloft, generic name sertraline, is a commonly used and effective antidepressant medication. It works by affecting the brain’s metabolism of serotonin, a brain chemical, or neurotransmitter. Typically, Zoloft requires about 3-4 weeks of consistent and regular dosing before any antidepressant effect can be expected. Once stopped the half-life of the medication (or, time it takes for 50% of the medication to be cleared from the body) is about 26 hours. One of the drug’s metabolites, or chemicals that the body converts Zoloft into, has a half life of 62 to 104 hours; thus, some of the medications effects will last for several days after the medication has been stopped. Among the reported effects and uncommon side effects of Zoloft in the Physician’s Desk Reference are agitation, nausea and/or vomiting, diarrhea, heartburn due to acid reflux, tremor, dizziness, insomnia, increased sweating, dry mouth, and sexual dysfunction. Although confusion is listed amongst the possible rare side effec
