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You stated that titers could be drawn if MMR and varicella were given at inappropriate intervals. Can a titer be drawn to determine if varicella vaccine was effective?

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You stated that titers could be drawn if MMR and varicella were given at inappropriate intervals. Can a titer be drawn to determine if varicella vaccine was effective?

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Antibody resulting from vaccination is generally of lower titer than antibody resulting from varicella disease. Commercial antibody assays, particularly the LA test, may not be sensitive enough to detect vaccine-induced antibody in some recipients. Because of the potential for false-negative serologic tests, routine postvaccination serologic testing is not recommended.

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