Yes, pomelos do seem to interact with medications similarly”
“Evidence now exists for pummelos (pomelos) to cause similar drug interactions to grapefruit. More exotic grapefruit hybrids such as tangelos, have not been directly studied, and since they are not commonly seen in the marketplace, may never be studied. However, these products are genetically derived from grapefruit originally, and therefore may have potential for drug interactions.” Sources: http://www.powernetdesign.com/grapefruit/general/faq.