Would you recommend treatment for greater than 1 year with clopidogrel following an episode of ACS?
Patients in CURE were treated for a minimum of 3 months or a maximum of 1 year (with a mean duration of 9 months) post randomization. Therefore CURE does not provide data on patients who were treated for greater than 1 year post ACS. The benefits of clopidogrel were observed early, i.e. within the first 30 days and from the period greater than 30 days after randomization to the end of follow up. There was incremental benefit in treating patients with clopidogrel longer than 30 days after randomization.
