Would you consider the protein creatinine ratio the best available screening technique for renal damage in these circumstances?
DR. PORTMAN: I do from a clinical standpoint. Obviously from a research standpoint you know to do timed urines or 24-hour urines you know would probably be more accurate but trying to simulate what we would do on a clinical basis I think it is the best that we have and the National Kidney Foundation has a statement in their guidelines that this is what should be used for all ages, children as well as adults. So, I do think that it is the most accurate that we currently have available. DR. ALLEN: Thank you. Dr. Portman, as we move through the discussion I will try to remember periodically to invite you specifically into the conversation but I think you can try to talk over us if you need to or want to weigh in at any point with a question or a comment. DR. PORTMAN: Okay, I would appreciate that. I do have at some point some questions to make. Since I have your attention are we allowed to talk to the sponsor still or not? DR. ALLEN: Yes, my understanding is that we can ask questions of t
