Would bone loss cause a rise in alkaline phosphatase?
Answer Hello Connie: Many bone diseases cause raised alkaline phosphatase levels. Some of the conditions are: Osteomalacia…where bones become soft as calcium and phosphorus leak out Pagets disease: where bone is constantly replaced as bone tissue is broken down, reabsorbed and rebuilt. Bone tumors, fractures etc Also if a person has Hyperparathyroidism…leading to increased secretion of parathyroid hormone. This produces excess calcium in blood. Bone damaged by cancer can raise blood calcium levels.
