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Will the untranslated mRNA with Riboswitch be degraded in the cell?

April 26, 2017CELL degraded mrna riboswitch untranslated

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Will the untranslated mRNA with Riboswitch be degraded in the cell?

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A. When a cell is in a bad environment(in our device, theophylline is toxic for E. coli.), the speed of mRNA degration is slower than under normal condition. Even though less mRNA with riboswitch is degraded, we still use a constitutive promoter to ensure that a greater amount of RNA is produced.