Will opening in safe mode definately work?
No problem with starting in safe mode, but I`ve just read your other question, try this to get rid of your infections. Try to download malwarebytes in safe mode with networking (F8 at startup) Rename the mbam-setup.exe to userinit.exe (right click the file and rename) if this doesn`t work try this solution. Download malwarebytes using another computer to memory stick/external/ disc. After you you click to download, click save instead of run, when box opens up click computer and then click the drive you want it to be saved to. Before saving it rename the mbam-setup.exe to userinit.exe Remove the disc/memory card, place in your infected computer, then run the set up. Start up in safe mode (F8) to run the setup. Do the quick scan first, followed by the full scan. Turn off system restore before you scan if the virus hasn`t already disabled it.