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Will looking at toluidine blue sections distort my ability to read H&E sections?

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Will looking at toluidine blue sections distort my ability to read H&E sections?

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No. The vast majority of slides you will look at over the course of your residency will be stained with H&E. Most specimens that are examined at the frozen section lab are reviewed the next day after the tissue has been processed in a traditional manner and stained with H&E. This allows a level a quality assurance by confirming the frozen section diagnosis and provides the resident and fellow with an opportunity to review their previous day’s work. Furthermore, toluidine blue is only used at the frozen section lab, in which you will spend only 8 months during your residency. During all of your other rotations H&E is the standard stain.

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