Why would hypertonic saline lower intracranial pressure?
Our housestaff were now able to avoid obvious pitfalls. They reasoned that to lower intracranial pressure, they would have to draw water out of the skull, not just out of brain cells (Figure 7).7 Therefore, the tonomole added must remain within the vascular space and not enter the brain ECF compartment. On hearing this, Professor Krebs beamed with satisfaction, enjoying the rewards due to a truly gifted teacher.
