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Why were the antidepressants bupropion and paroxetine chosen for this study?

April 26, 2017antidepressants bupropion chosen paroxetine study

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Why were the antidepressants bupropion and paroxetine chosen for this study?

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A. Several antidepressants are used to treat depression associated with bipolar disorder. Bupropion (sustained-release formula) and paroxetine were chosen because they are commonly used for patients with bipolar-related depression. Compared to some other antidepressants, bupropion and paroxetine are less frequently associated with “treatment-emergent affective switch,” a term used to describe bipolar patients’ mood changes between depression and mania.