Why was zinc finger nuclease (ZFN) technology so crucial?
ZFN technology provides researchers with the ability to target and precisely manipulate the genome of eukaryotic organisms to produce permanent and heritable changes. This technology enables scientists to build entirely new animal models and grow cell lines or entire organisms faster and more efficiently than with conventional technology. Q4: How have researchers across the globe responded to the breakthrough? Those familiar with ZFN technology were happy to see it come to market last year via our CompoZr ZFN platform. Those same researchers are even more excited to see its potential for a very practical application: knockout rats for disease research. Researchers in the pharmaceutical and biotech industries in particular, who know the current limitations in both targeted gene editing and biological models for disease research, have been eager to see how well our knockout models perform. I think the greater scientific community has been interested to see where else this technology and
