Why was fenfluramine withdrawn?
Mayo Clinic reported in 1997 that they had seen 24 patients that developed heart valve disease from taking Fen Phen. The valves of the patients who had the valve replacement surgery had similar diseased valves to carcinoid syndrome, indicating a correlation between Fen Phen and valve disease. The FDA later issued a Public Health Advisory describing what the Mayo Clinic had found with Fen Phen.
