Why should we use fracture mechanics to study transdermal devices?
In order for a transdermal patch to be effective, satisfactory adhesion to the dermal layer must be maintained. This requires that there be adequate initial adhesion as well as appropriate long-term adhesion. A fracture mechanics approach to the study of the interface between the adhesive material and the dermal layer enables the quantification of the adhesive properties of the system and permits a means to determine the effects of such varied parameters as strain rate, temperature, humidity, physiological environment, and layer thickness on adhesion and device failure. Our research considers that the resistance to interface debonding may be quantified in terms of the interfacial fracture energy, G, and is a property of the system. This analysis accounts for both the work of adhesion as well as the viscoelastic constitutive behavior of the soft adhesive layer. Predictive bridging mechanics models are incorporated into this research in order to study cavitation in the PSA and the develo
Related Questions
- Most field mechanics/technicians have small hoisting devices on their service trucks, typically in the 4,000 - 10,000 pounds capacity range. Do these mechanics/technicians need to be certified?
- Has a study or research of New Zealand medical devices been undertaken to compare differences with Australia?
- What devices will be used in the study?
