Why should PCR products from representative mumps cases and mumps viral isolates be submitted to CDC for sequence analysis?
The sequence of the PCR product will confirm positive PCR reactions. In addition, the sequence of the mumps short hydrophobic (SH) gene is used to assign mumps viruses to one of 12 recognized genotypes. The sequence information will help to identify the source of the virus, and can provide confirmation of suspected epidemiologic links.