Why should leukocyte results be verified with microscopy?
Studies in cats show that leukocyte esterase tests are nonspecific for the detection of pyuria, which means that most urine will be positive for leukocytes when none are present. In both dogs and cats, leukocyte esterase tests are insensitive for the detection of pyuria, which means that urine can be negative for leukocytes when leukocytes are present.