Why should I measure NT-proBNP instead of using clinical criteria for the diagnosis of heart failure?
Several studies have shown that NT-proBNP is elevated in patients with ventricular dysfunction and its level correlates with the severity of heart failure (New York Heart Association Classification, NYHA). In contrast to clinical criteria, NT-proBNP is a sensitive marker for cardiac function. Elevated NT-proBNP levels indicate the presence of an underlying cardiac disorder that requires further investigation, especially in early stages of ventricular dysfunction.