Why sequence DNA?
• Sequencing DNA gives us the ability to massively digitize the genetic codes and discover SNPs and other forms of mutations in the genome. This can increase our understanding, diagnosis, treatment and prevention of disease. • Comparative resequencing (analyzing variations across and within species or samples subjected to different treatments) enables genome-wide association studies and provides a more comprehensive understanding that can enable development of personalized medicines and clinical diagnostic. • De novo sequencing has applications for medical, pharmaceutical, forensics, identification, defense, and basic research. • Transcriptome sequencing gene expression profiling, exon sequencing, trans-splicing RNA sequencing, identification of novel transcripts, splice variant detection, transcriptional mutation, miRNA, small RNA, non-coding RNA, etc.
