Why not just make biologists learn Excel/Access?
Many biologists do use Excel, but they might not use fancy functions or macros. The interface may not work for occasional users, or they may feel that learning an “advanced” program like Access is a waste of time. And while Excel and Access can do many of the jobs the Scriptome does, they are not designed to handle FASTA formats, for example. (Excel 2003 will also choke on files with more than 65535 rows, and won’t merge files without VB programming.