Why not implant the tumor cells in dogs after they are born?
An advantage of implanting the tumor cells into the dogs during fetal development is that their immune systems are left intact, an important and unique feature that makes Dr. Berens’ model similar to human glioma. Past research has suggested that glioma can be successfully implanted into dogs during the first day or two after birth. However, these animals die from their tumors more quickly than do rodents B (sic) thus the time frame for studying tumor growth and treatments in these animals is not adequate. In adult dogs, the tumor cells are typically rejected by the immune system. There are ways that a dog’s immune system can be suppressed to allow the tumor cells to grow B (sic) but the resulting animal model would not be representative of the typical human glioma patient. Dr.
