Why no relationship found between protease inhibitors and glucose intolerance?
“Using an oral glucose tolerance test, we found that non-protease inhibitor HAART, and not protease inhibitor-HAART was associated with impaired glucose tolerance and insulin resistance”, write the investigators. The investigators suggest that the association between opiate use and glucose intolerance could be a marker for hepatitis C virus infection, a risk factor for diabetes that was not assessed in the study. They conclude by recommending that all HIV-positive women, with risk factors for diabetes, should be screened by their HIV care providers for the presence of the condition.
