Why MHC Tetramers?
MHC Tetramer technique has become a “gold standard” for the quantification of CD8+ T cell immune responses. The development of this technique has revolutionized the study of T cell immune responses. The acceptance of the method is indicated by the number of citations to key papers describing the method: the original Science paper describing the method has been cited 500 times. By offering exquisite antigen specificity and sensitivity, it is suitable for basic and clinical study in a number of applications including drug / vaccine development.
