Why measure pressure rather than velocity, or are both necessary?
The choice of method depends on what you want to see. As an interventional cardiologist, wanting to know if a patient has been helped by a coronary intervention, it is the epicardial lesion that is of interest and not the small vasculature (which cannot be treated with a balloon). In this case, pressure measurement is the preferred method. Velocity measurement has the limitation of having no accepted normal value and of being more affected by the homodynamic state and by other conditions such as small vessel dysfunction. The PressureWire Sensor is a more accurate measure of epicardial disease. To detect and quantify small-vessel disease, the combination of pressure and flow velocity measurement is necessary. This could, at least theoretically, be a limitation of the concept of pressure-derived Fractional Flow Reserve.
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- Why measure pressure rather than velocity, or are both necessary?
