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Why isn’t “titer” important with the advent of newer more modern ANA testing?

April 26, 2017advent ANA isn’t Modern newer Testing

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Why isn’t “titer” important with the advent of newer more modern ANA testing?

1 Answer

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10 Posted

Titer is a means to improve the specificity of an IFA ANA test. The higher the titer the better the positive predictive value of the IFA ANA. If one uses a “more specific” test for relevant antibodies set to “clinical cutoffs” then the titer is irrelevant.