Why is there a difference between the ways the same functional group glows on two different molecules?
The Glowing Molecule visualisation shows an analysis of the strongest structural influences on the property of each individual molecule. More specifically, it assesses the sensitivity of the property to the presence of each atom or functional group. For a linear model a functional group would have the same influence, irrespective of the molecule in which it occurred. However, the link between structure and property is rarely linear, as the influence of a functional group will depend on the structural characteristics of the entire molecule. Therefore, the glow for a specific functional group may vary from molecule to molecule depending on the presence of other functionalities.
