Why Is Smoking Addictive?
Nicotine The substance found in tobacco that causes addiction. is the drug in tobacco that causes addiction. It is absorbed and enters the bloodstream, through the lungs when smoke is inhaled, and through the lining of the mouth (buccal mucosa) when tobacco is chewed or used as oral snuff or for non-inhaled pipe and cigar smoking. It is also absorbed through the nose from nasal snuff, which was popular in the 18th century.