Why is skim milk powder used while reconstitution of live vaccines? What is the quantity that is used?
Since live vaccines are prepared from attenuated live viruses, skimmed milk powder acts as a stabilizer to protect the virus from adverse effects. Skimmed milk powder is added @ 6 grams/liter of water for drinking water vaccination. • Why are killed vaccines not stored in the freezing chamber of a refrigerator? Killed vaccines are not stored in the freezing chamber in order to prevent breaking/separation of emulsion, which results in uneven release of antigen, and thereby improper immune response. • Why it is necessary to vaccinate the birds during cool hours of the day, especially when using live vaccines? Since viruses are thermolabile, it is essential to carry out live vaccination at low temperatures, hence vaccination is done during the cooler hours of a day. • For how many hours are birds deprived of water, before giving vaccines through drinking water? This depends on the season, ambient temperature and agro-climatic zone. As a general guideline, it is advisable to withdraw water
