Why is progesterone most effective when delivered as a skin cream?
Transdermal skin absorption has been found to be the most efficient means of introducing Natural Progesterone to the body. Research has proven that pills are not effectively and reliably absorbed through the stomach and intestines due to varying conditions such as gut health, food content, acids and alkalines, fat-to-bile contact and liver metabolism of a fat-soluble hormone. When comparing progesterone cream applied to the skin to that of a pill, it would require nearly ten times the quantity orally to equal that of the cream. Oral doses would also be subject to liver interaction, while a skin cream dose of progesterone will by-pass the liver on its first cycle through the body.
