Why is prenatal diagnosis recommended after PGD?
• Although PGD has been performed for years, the technology is still considered investigational • Risk of chromosome mosaicism For these reasons prenatal diagnosis through chorionic villus sampling (CVS) or amniocentesis is recommended to confirm the results • Chorionic Villus Sampling (CVS) Chorionic villus sampling (CVS) is typically performed in the first trimester of pregnancy, between 10 and 12 weeks gestation, by a specially trained obstetrician or perinatologist who removes a small amount of tissue, called chorionic villi, from the placenta either via a catheter placed through the cervix or a thin needle placed through the abdomen. The cells in this tissue come from the same cells that created the fetus and, thus, should have the same chromosome make-up. The cells are tested for chromosome abnormalities. • Amniocentesis Amniocentesis is usually done in the second trimester of pregnancy, between 15 and 20 weeks of pregnancy, by a specially trained obstetrician or perinatologist w
