Why is Pluset measured in units of biological activity?
Extractions from biological substrates give different performances, depending on the original raw material, which will present slight variations (depending on the age and gender of the animal, season, etc.). Some gonadotropin products express hormonal content in mg per unit of volume, which is measured by radio-immunoassay (RIA), an analytical technique that employs antibodies to FSH and LH. These hormones, however, as well as their metabolites, may have several isoforms, some of which are biologically active while others are inactive. It is also known that other hormones such as hCG or PMSG, may show a high degree of FSH or LH activity by bio-assay, which will not be indicated by RIA, due to the lack of recognition of these hormones by FSH or LH anti-bodies.
