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Why is perchlorate harmful?

Harmful perchlorate
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Why is perchlorate harmful?

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Perchlorate interferes with iodide uptake into the thyroid gland, and the thyroid is a central control point for a variety of hormonal responses. In fetuses, infants, and young children, thyroid hormones are critical for normal growth and development. In adults, the thyroid helps to regulate metabolism and fertility. Iodide deficiency in women (such as that caused by perchlorate exposure) can decrease levels of fertility, increase miscarriage rates, and lead to more serious health risks such as goiter and thyroid cancer. Women with iodide deficiency who are lucky enough to become pregnant have a high risk of birthing babies with developmental problems-including behavioral disorders, delayed development and decreased learning capability. Nursing women can excrete perchlorate in breastmilk in disproportionately high quantities, resulting in infant consumption of perchlorate at levels that far exceed the recommended limit per body weight. Kirk et al. (2005) analyzed 36 breast milk samples

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