Why is particle size of Beta glucan oral supplements important?
Beta glucans are absorbed through the intestine wall and then ingested by the Macrophage immune cells via Beta glucan receptors of approximately one micron in size. Large particle or globular size Beta glucans are inexpensive because they are minimally processed and not reduced to microparticulate size of 1 to 2 microns particle size for superior immune response potentiation. After transferal from the intestine to the lymphatic system in the Peyers Patch, the Beta glucan must be ingested by immune cells known as Macrophages. T cells, NK cells and B cells are in turn potentiated in what is called the immune cascade. Beta glucan consumption is easier with more Beta glucan ingested faster if in microparticulate bits the size of the receptor sites, in contrast to large chunks or reaggregated clumps of glucan after exposure to water in the digestive process that hinder fast and complete ingestion. Finally, more immune cells will ingest the smaller particles in size, increasing the saturatio
